Category Archives: Biological Psychiatry

The Medicalization of Emotional Life

Jeremy Safran in “Psychiatry in the News“:

It is one thing to hypothesize that psychological and emotional problems are associated with changes at the biological level (e.g., specific patterns of brain activity or levels of neurotransmitters) or that symptom remission is associated with biological changes. It’s another to assume that the underlying causes of mental health problems are always biological in nature and that meaningful improvements in treatment will only take place when we can directly target the relevant brain circuitry. While it may be the case that biological factors play a more significant causal role in some mental health problems (e.g., schizophrenia) than others, the assumption that the major causal factor for mental health problems is always biological is a form of simplistic reductionism.

I want to be perfectly clear that I do not question the potential value of brain science research. What I do question is the single-minded emphasis on brain science research to the virtual exclusion of all other forms of mental health research. The new NIMH paradigm for research means that the amount of funding available for the development and refinement of treatments such as psychotherapy that are not targeted directly at the brain circuitry (although they do influence it indirectly), is likely to continue to shrink. It is important to recognize that funding priorities shape the programs of research pursued by scientists, and thus the type of research findings that are published in professional journals and disseminated to the public. This in turn shapes the curricula in psychiatry and clinical psychology training programs, which shapes the way in which mental health professionals understand and treat mental health problems. It also influences healthcare policy decisions and the type of coverage provided by third party insurers.

In concrete terms, the explicit NIMH policy shift is likely to mean that despite the large and growing body of evidence demonstrating that a variety of forms of psychotherapy (e.g., cognitive therapy, interpersonal psychotherapy, psychoanalytic therapy, emotion focused therapy) are effective treatments for a range of problems, we are likely to continue to see a decreasing availability of the already diminishing resources that can provide high quality psychotherapy for those who can potentially benefit from it.

Mind, Brain, and Mental Illness

Andrew Brown in “Depression is not a ‘brain disorder‘” in The Guardian

The mind is not just some decorative pattern read off the brain and mistaken for the real thing. Consciousness is not just the whistle on the steam train, as William James put it. Treating unhappiness as a problem in the brain is good for the profits of drug companies, but doesn’t actually make us all happier in the long run.

To say that the mind depends on the brain is easy enough – and true, so far as we know. But that doesn’t mean that they are the same thing, or that understanding the one will supply a sufficient understanding of the other. Talking about depression as a brain disease is a warning sign that someone has their ideas all wrong – and that’s not a problem with their brain.

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Biological Psychiatry, Psychodynamic Psychiatry, and a New Approach to Understanding Mental Illness

In Psychiatric Times, Dr. James Knoll IV writes in “The Humanities and Psychiatry: The Rebirth of Mind“:

What place do the humanities have in psychiatry? One might as well ask: What place does the mind have in the brain? What place does clinical experience have in medicine? What is the utility of the empty space within the vessel?…  In this article, I focus on the importance of the humanities to psychiatry, via the perennial conflict between biological psychiatry and psychodynamically oriented psychiatry. I hope to use a humanist approach to show that these “two cultures” depend on each other for balanced progress in the field…

Biological psychiatry has made truly impressive progress, yet it remains the case in 2013 that “biological psychiatrists do not hold the panacea for serious mental disorders,”particularly when standing on the lone pillar of science. The art of medicine remains a critical foundational structure in psychiatry, and both pillars are necessary for the stability of the field. One might say that the humanities and/or psychoanalytic thought helps provide science with the relevant questions on which to focus its “piecemeal work.”Put another way: the humanities provide the wonder, which science then illuminates.

It is sometimes the case that older theories are not proved false—rather, the very progress they contributed to now shows their limits.

In Mind, Modernity, Madness: The Impact of Culture on Human ExperienceLiah Greenfeld writes:

Today we know an awful lot about schizophrenia and manic-depressive illness. An enormous amount of information has been collected about the psychological and biological expressions of these diseases — about the personal experience and outward behaviors corresponding to them, the anatomical abnormalities which show themselves in certain groups of patients and neurochemical dynamics characteristic of others — about patterns of their transmission in families and certain genetic elements involved. But this information refuses to combine into a “case” — an explanatory argument based on the available evidence: there are gaping lacunae where pieces of the puzzle are supposed to dovetail; and none of the things we know can be said to constitute the smoking gun. We still do not know what causes these diseases and thus cannot either understand their nature or cure them. After two hundred years neither of the two approaches — the biological and the psychodynamic — in which psychiatry put its hopes brought these understanding and cure any closer. Therefore, I feel justified to offer a new – radically different — approach that has never been tried.

The historical recency, the timing of the spread in different societies, and the increase in the rates of mental disease of unknown etiology indicates that it cannot be understood in terms of any universal, biological or psychological, propensity of human nature, or explained by the characteristics of the individual human organism or personality as such. The observable trends (however incredible) pertain to and distinguish between specific societies and historical periods, and therefore must be accounted for historically. …

My intention is not to prove either the biological or the psychodynamic approach to mental disease wrong, but to complement them, adding to psychiatry a necessary element which has been heretofore missing. All the findings of the biological research, specifically, should be consistent with the approach I propose and, in cases they are not, the fault would lie with the approach rather than the findings. Culture, personality, and biology are different, but not mutually exclusive realities, and for this reason cultural, psychological, and biological arguments should not be mutually exclusive.